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Publications

 

2019

Shirazi J*, Morgan JT*, Comber EC, Gleghorn JP (2019) Generation and morphological quantification of large scale, three-dimensional, self-assembled vascular networks. MethodsX. 6:1907-1918

Morgan JT, Robbins AK, Mateson AB, Sawamoto K, Tomatsu S, Gray DR, Gleghorn JP, Barthold JS (2019) Regional Variation in Androgen Receptor Expression and Biomechanical Properties May Contribute to Cryptorchidism Susceptibility in the LE/orl Rat. Frontiers in Endocrinology. 9:738.

26.  Morgan JT*, Shirazi J*, Comber EM, Eschenburg C, Gleghorn JP (2019) Fabrication of centimeter-scale and geometrically arbitrary vascular networks using in vitro self-assembly. Biomaterials. 189:37-47

2018

Morgan JT*, Stewart WG*, McKee RM, Gleghorn JP (2018) The mechanosensitive ion channel TRPV4 is a regulator of lung development and pulmonary vasculature stabilization. Cellular and Molecular Bioengineering. 11(5):309-320

Melamed JR, Morgan JT, Gleghorn JP, Sims-Mourtada J, Day ES (2018) Investigating the role of Hedgehog/GLI1 signaling in glioblastoma cell response to temozolomide. Oncotarget. 9:27000-27015. PMID: 29930746

Thomasy SM, Raghunathan VK, Miyagi H, Evashenk AT, Sermeno JC, Tripp GK, Morgan JT, Murphy CJ (2018). Latrunculin B and substratum stiffness regulate corneal fibroblast to myofibroblast transformation. Exp Eye Res. 170:101-107. PMID: 29421383

2017

Raghunathan VK, Eaton JS, Christian BJ, Morgan JT, Ver Hoeve JN, Yang CYC, Gong H, Rasmussen CA, Miller PE, Russell P, Nork TM, Murphy CJ (2017). Biomechanical, ultrastructural, and electrophysiological characterization of the non-human primate experimental glaucoma model. Scientific Reports. 7(1):14329. PMID: 29085025

2016

Gilbert RM, Morgan JT, Marcin ES, Gleghorn JP (2016). Fluid Mechanics as a Driver of Tissue-Scale Mechanical Signaling in Organogenesis. Current Pathobiology Reports. 4(4):199-208. PMID: 28163984

Raghunathan VK, Morgan JT, Russell P (2016) Biomechanics and the aqueous humor outflow pathway, In: Glaucoma Research and Clinical Advances 2016 to 2018:121

2015

Raghunathan VK*, Morgan JT*, Park SA, Weber D, Phinney B, Murphy CJ, Russell P (2015). Dexamethasone stiffens trabecular meshwork, trabecular meshwork cells and matrix. Investigative Ophthalmology & Visual Science. 56(8):4447-4459

Morgan JT*, Raghunathan VK*, Chang Y, Murphy CJ, Russell P (2015). The intrinsic stiffness of human trabecular meshwork cells increases with senescence. Oncotarget, 6(17):15362-74.

Morgan JT, Kwon HS, Wood JA, Borjesson DL, Tomarev SI, Murphy CJ, Russell P (2015). Thermally labile components of aqueous humor potently induce osteogenic potential in adipose-derived mesenchymal stem cells. Experimental Eye Research, 135:127-33.

Morgan JT*, Raghunathan VK*, Chang Y, Murphy CJ, Russell P (2015). Wnt inhibition induces persistent increases in intrinsic stiffness of human trabecular meshwork cells. Experimental Eye Research, 132:174-8

Raghunathan VK*, Morgan JT*, Chang Y, Weber D, Phinney B, Murphy CJ, Russell P (2015). Transforming growth factor beta 3 modifies mechanics and composition of extracellular matrix deposited by human trabecular meshwork cells. ACS Biomaterials Science & Engineering, 1(2):110-118

2014

Raghunathan VK, Dreier B, Morgan JT, Tuyen BC, Rose BW, Reilly CM, Russell P, Murphy CJ (2014) Involvement of YAP, TAZ and HSP90 in Contact Guidance and Intercellular Junction Formation in Corneal Epithelial Cells. PLoS ONE 9(10): e109811

Chang Y, Raghunathan VK, Garland SP, Morgan JT, Russell P, Murphy CJ (2014). Automated AFM force curve analysis for determining elastic modulus of biomaterials and biological samples. Journal of the Mechanical Behavior of Biomedical Materials, 37:209-18

Morgan JT, Wood JA, Walker NJ, Raghunathan VK, Borjesson DL, Murphy CJ, Russell P (2014). Human Trabecular Meshwork Cells Exhibit Several Characteristics of, but Are Distinct from, Adipose-Derived Mesenchymal Stem Cells. Journal of Ocular Pharmacology and Therapeutics, 30(2-3):254-66

Morgan JT*, Raghunathan VK*, Thomasy SM, Murphy CJ, Russell P (2014). Robust and artifact-free method of mounting tissue samples for atomic force microscopy. Biotechniques. 56(1):40-42

Zimmer C, Liu Y, Morgan J, Yang G; Wang K, Kennedy I, Barakat A, Liu G (2014). A New Approach to Investigate the Cytotoxicity of Nanomaterials Using Single Cell Mechanics. Journal of Physical Chemistry B, 118(5):1246-55

2013

Morgan JT, Murphy CJ, Russell P (2013). What do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease. Experimental Eye Research, 115C:1-12

Thomasy SM, Morgan JT, Wood JA, Murphy CJ, Russell P (2013). Substratum Stiffness and Latrunculin B Modulate the Gene Expression of the Mechanotransducers YAP and TAZ in Human Trabecular Meshwork Cells. Experimental Eye Research, 113:66-73

Dreier B, Gasiorowski JZ, Morgan JT, Nealey PF, Russell P, Murphy CJ (2013). Early responses of vascular endothelial cells to topographic cues. American Journal of Physiology - Cell Physiology, 305(3):C290-8

2012

Raghunathan VK*, Morgan JT*, Dreier B, Reilly CM, Thomasy SM, Wood JA, Ly I, Tuyen BC, Hughbanks ML, Murphy CJ, Russell P (2012). Role of substratum stiffness in modulating genes associated with extracellular matrix and mechanotransducers YAP and TAZ. Investigative Ophthalmology & Visual Science, 54(1):378-86.

Aksenov AA, Gojova A, Zhao W, Morgan JT, Sankaran S, Sandrock CE, Davis CE (2012). Characterization of volatile organic compounds in human leukocyte antigen heterologous expression systems: a cell's "chemical odor fingerprint". Chembiochem. 2012 May 7;13(7):1053-9

Morgan JT*, Wood JA*, Shah NM, Hughbanks ML, Russell P, Barakat AI, Murphy CJ (2012). Integration of Basal Topographic Cues and Apical Shear Stress in Vascular Endothelial Cells. Biomaterials, 33(16):4126-35

2011

Morgan JT, Pfeiffer ER, Thirkill TL, Kumar P, Peng G, Fridolfsson HN, Douglas GC, Starr DA, and Barakat AI (2011). Nesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarization. Molecular Biology of the Cell, 22:4324-4334. PMID: 21937718

2008

Zhao W, Morgan JT, Davis CE (2008). Gas Chromatography Data Classification Based on Complex Coefficients of an Autoregressive Model. Journal of Sensors 2008: 1-8.

2007

Fehrenbacher N, Aldredge RC, Morgan JT (2007). Turbulence structure in a Taylor-Couette apparatus. Experimental Thermal and Fluid Science, 32(1):220-230.